Iran sees no prospect of negotiations with the US, a foreign ministry spokesman said on Tuesday, a day after US President Donald Trump said a deal with Tehran on its nuclear program was possible.

Washington withdrew last year from a 2015 international nuclear deal with Tehran, and is ratcheting up sanctions in efforts to strangle Iran's economy by ending its international sales of crude oil.

Trump said on Monday: "I really believe that Iran would like to make a deal, and I think that's very smart of them, and I think that's a possibility to happen."

Asked about Trump's comments in a news conference in Tehran, Iranian Foreign Ministry spokesperson Abbas Mousavi was quoted as saying by the semi-official Fars news agency: "We currently see no prospect of negotiations with America."

"Iran pays no attention to words; What matters to us is a change of approach and behavior."

Trump also said that US was not looking for regime change in Iran, adding that "we are looking for no nuclear weapons."

Iranian Vice President Eshaq Jahangiri said on Tuesday the country was not allowed to pursue the development of nuclear weapon as this was banned by Supreme Leader Ayatollah Ali Khamenei, Iran's highest authority.