China on Wednesday expressed strong dissatisfaction and firm opposition to US interference in Hong Kong's internal affairs, urging the US to respect China's concerns.

Chinese foreign ministry spokesman Hong Lei made the remarks regarding a meeting between US Vice President Joe Biden and two former Hong Kong legislators.

Biden underscored long-standing US support for democracy in Hong Kong and for the city's high degree of autonomy under the "one country, two systems" framework, said the White House statement.

Since Hong Kong's return 17 years ago, the region has seen remarkable achievements in implementing the "one country, two systems" framework, the spokesman said.

"What the United States has done was absolutely wrong," Hong added.